When inquiring about Rejuran in South Korea, common names include Rejuran Healer, Rejuran HB plus and Rejuran I. The three are not simply a “basic version, enhanced version” relationship; their main differences lie in product specifications, formulation composition, and common areas of use.
When choosing, you should first clarify the area you want to improve and your main concerns, then decide based on your pain sensitivity, acceptable recovery period, required dosage, and the doctor’s injection plan. The product name is only part of the treatment plan and cannot replace an in-person consultation.
Quick Summary
The standard Rejuran is commonly used for overall facial skin texture and fine line management; Rejuran I has an official specification of 1cc and is often used on thinner areas or areas requiring precise treatment such as the periorbital and perioral regions; Rejuran HB plus comes in a 1mL specification and contains hyaluronic acid and lidocaine in addition to PN, making it more suitable for people who also value hydration and are concerned about injection pain. The specific areas, dosage, and treatment course should still be evaluated by a doctor.
What is Rejuran?
Rejuran is the common Chinese name for the Rejuran brand. Its core products use PN, or polynucleotide ingredients, which are injected subcutaneously for the temporary improvement of facial wrinkles. Different models differ in formulation, packaging specifications, and recommended areas of use.
“Water-light injection”, “skin nutrient injection” and “Rejuran” are not exactly the same concept. Water-light or skin nutrient injections can generally refer to various injectable skin management solutions, while Rejuran is one specific brand. When consulting, you should confirm the full product name instead of only asking “do you offer water-light injections”.
What is the difference between Rejuran Healer, HB plus and periorbital Type I?
| Product | Official Specifications and Formulation | Key Considerations for Selection |
|---|---|---|
| Standard Rejuran Often called Healer or Black Box | 2cc per vial, PN formulation; 2 vials per box. | Commonly used for overall facial skin texture, elasticity, and fine line management. The dosage to be used needs to be confirmed based on whether the treatment covers the full face or a local area. |
| Rejuran HB plus | 1mL per vial, containing PN, hyaluronic acid, and lidocaine. | You can discuss it with your doctor if you also value hydration or are worried about injection pain. The presence of lidocaine does not mean the procedure will be completely painless. |
| Rejuran I Periorbital Type I | 1cc per vial, PN formulation. | Officially listed areas of use include facial areas such as the periorbital and perioral regions, and may also include areas like the neck; it is often used on thinner areas and areas requiring precise injection. |
Different clinics may use inconsistent Chinese names. For example, “black box”, “white box”, “red box”, and “eye version” are marketing nicknames for easy identification; when making an appointment and paying, you should still refer to the full English product name, packaging, and per-vial volume.
What needs is the standard Rejuran suitable for?
Official product information for the standard Rejuran shows that it has a PN formulation with a specification of 2cc per vial, and is mainly used for the temporary improvement of facial wrinkles. In clinical consultations, doctors will also assess suitability based on skin texture, elasticity, dryness, fine lines, and overall skin condition.
If you wish to treat the full face, the key point is not just “whether to choose the black box”, but also to confirm:
Whether the planned treatment covers the full face or a local area;
How many cc and how many vials will be used in total;
how the dose is distributed across areas such as the forehead, both cheeks, under the eyes, and around the mouth;
whether manual injection or another injection method is used;
whether it is combined with other products or devices;
whether the quoted price includes anesthesia, needles, aftercare, and VAT.
Even with 2 cc, the experience and recovery may differ if the treatment area and distribution method vary. Dosage should not be determined solely by fixed templates found online.
What is the difference between Rejuran HB plus and the standard version?
Rejuran HB plus has an official specification of 1 mL per vial, and its formula includes PN, hyaluronic acid, and lidocaine. Hyaluronic acid is related to hydration, while lidocaine is a local anesthetic, so HB plus is often chosen by people who want both hydration and reduced injection discomfort.
However, "containing lidocaine" does not mean the treatment is completely painless. The number of needle pricks, injection depth, treatment area, injection speed, anesthesia method, and individual sensitivity all affect the actual experience.
Before choosing HB plus, you should also actively inform your doctor if you have an allergy to lidocaine or other local anesthetics. If your goal is a full-face treatment, also confirm whether 1 mL is the planned total dose, or if multiple vials or a combination with other products is needed.
Can the periorbital Type I only be injected under the eyes?
No. The official product information for Rejuran I lists areas of use including the face, especially the eye and mouth areas, as well as the neck, décolletage, and hands. In actual treatments, it is often used on thinner areas or areas requiring precise injection.
Fine lines under the eyes, dry lines, dark circles, under-eye bags, and tear troughs may look similar, but their causes are not the same. Rejuran cannot replace a proper assessment of pigment, blood vessels, structural hollows, fat protrusion, or skin laxity. During a consultation, your main concerns should first be identified before deciding whether periorbital Type I is suitable, or if other treatment approaches are needed.
The skin around the eyes is thin and rich in blood vessels, so swelling, needle marks, or bruising after injection may be more noticeable. Allow time for recovery before important events or return flights.
How to choose based on your needs?
For comprehensive full-face skin texture and fine line management:You can first ask about the standard Rejuran, and confirm the full-face dose required and injection zones.
If you are mainly concerned with precise areas such as around the eyes or mouth:You can ask about Rejuran I, but first distinguish between fine lines, pigment, vascular, and structural issues.
If you want hydration and are sensitive to injection pain:You can discuss Rejuran HB plus with your doctor, and also confirm any allergy history related to lidocaine.
If you have hollows, prominent under-eye bags, or deep scars:Do not choose a product on your own based only on the name; a doctor should assess the depth of the issue and other available options.
The manufacturer’s product line also includes models such as Rejuran S. If a quotation includes names other than the standard version, I, or HB plus, ask the clinic to provide the full product name, specifications, and planned treatment areas, rather than judging solely by the box color.
Does a higher dose always mean more noticeable improvement?
Dosage is related to the treatment area, but more is not always better. The volume needed for a full face differs from that for a localized periorbital area, and the same volume can result in different treatment designs depending on the injection depth and distribution of injection points.
When inquiring about dosage, it is recommended to replace the question "how much for 2 cc" with the following questions:
What is the full name of the product being used?
What is the volume per vial? How many vials and how many cc will be used in total?
Which specific areas will be injected? How will the dose be distributed across each area?
Will the unopened packaging be shown on site and the expiration date checked?
Will there be an in‑person consultation and the injection performed by a doctor?
Does the quoted price include anesthesia, consumables, post‑treatment care, and VAT?
What reactions are common after Rejuran treatment?
After the injection, you may experience needle marks, localized bumps, redness, swelling, tenderness, or bruising. The severity and duration of these reactions are affected by the product’s viscosity, injection dose, treatment area, injection method, and individual constitution. Most symptoms gradually subside, but recovery time cannot be stated as a fixed number of days for everyone.
After treatment, follow the care instructions provided by your doctor. General points to note include:
Do not squeeze, massage, or rub the injection area on your own;
The timing for washing your face and applying makeup depends on the condition of the needle marks and the clinic’s instructions;
Avoid alcohol, strenuous exercise, saunas, and high‑temperature environments for a short period;
Maintain gentle cleansing and sun protection, and temporarily pause irritating skincare products;
Keep a record of the product name, dose, treatment date, and the clinic’s contact information.
If you experience worsening pain, noticeable changes in skin color, blisters, rapidly expanding swelling, breathing discomfort, or other abnormal symptoms, contact the treatment clinic immediately and seek nearby medical attention promptly if needed.
What conditions should be mentioned to the doctor in advance?
Before the consultation, be honest about any previous injections or laser treatments, medications you are currently taking, allergy history, chronic illnesses, and your recent skin condition. In particular, be sure to mention:
A history of allergy to fish, salmon‑derived ingredients, or related products;
Allergy to lidocaine or other local anesthetics;
Current use of anticoagulants or medications that affect blood clotting;
Infection, obvious inflammation, open wounds, or herpes in the treatment area;
Pregnancy, planning for pregnancy, or breastfeeding;
Immune system disorders, a tendency to form severe scars, or other significant medical history.
These conditions do not necessarily mean treatment is absolutely contraindicated, but they will affect risk assessment, treatment timing, and product selection, and should be evaluated individually by a doctor.
What can I prepare before consulting about Rejuran at B:AID?
To make the online consultation more efficient, you can prepare front‑ and side‑view photos taken in natural light without filters, and explain the areas you most want to improve, previous treatments, allergy history, acceptable recovery time, and how long you will be staying in Seoul.
It is also recommended to ask customer service to confirm in writing the full product name, volume per vial, estimated number of vials, injection sites, treating doctor, total price including tax, and post‑treatment contact information. Online communication can help you understand pricing and scheduling, but final suitability and the actual dose must be determined through an in‑clinic consultation.
Frequently Asked Questions
Is Rejuran Healer the same as Rejuran Black Box?
In Chinese‑language consultations, the standard Rejuran is often called Healer or Black Box. To avoid confusion from inconsistent naming across clinics, verify the full English name, packaging, and official specification of 2cc per vial before making payment.
Is HB plus more effective than the standard version?
They cannot be compared that simply. HB plus and the standard version differ in formulation and specification. HB plus contains added hyaluronic acid and lidocaine, so key factors in choosing it include moisturization needs and pain sensitivity; the standard version is commonly used for comprehensive facial treatment. The more suitable product depends on the treatment area, your goals, and the doctor’s treatment plan.
Can the Periocular Type I improve dark circles?
Dark circles may be related to pigmentation, blood vessels, thin skin, tear trough depression, shadow from under‑eye bags, or a combination of factors. Periocular Type I is not suitable for all types of dark circles; the main cause should be identified first.
How many cc of Rejuran are needed per treatment?
There is no fixed dose that works for everyone. The required volume varies for the full face, both cheeks, the eye area, or localized fine lines, and also depends on skin condition and injection design. You should confirm the volume per vial, total number of vials, and specific injection zones.
Does the lidocaine-containing HB plus cause no pain at all?
No. Lidocaine can help reduce some pain, but the needle pricks, treatment area, injection method, and individual sensitivity will still affect the experience. The anesthesia plan should also be assessed by a medical professional.
Can Rejuran be done on the same day as other treatments?
Some regimens may be combined, but whether they are suitable for the same day depends on the treatment area, skin condition, type of energy-based device, injection depth, and recovery period. Do not add treatments on your own; the order and interval should be determined by a doctor during consultation.
This article is for general product information only and does not replace a doctor's consultation, diagnosis, or individualized medical advice. The type, dose, injection site, administration method, and treatment course of Rejuran should be determined by a doctor based on medical history and in-person assessment. Product information, pricing, and clinic arrangements may change; please reconfirm before booking and payment.



